Associate Scientist USP (Bacterial Processes)

Vacancy number: A2300065
Janssen Vaccines & Prevention - Leiden (Nederland)

For our client, Janssen Vaccines & Prevention, we are looking for an Associate Scientist USP (Bacterial Processes).


  • Bacteria
  • Recombinant antigen expression
  • BSL I/II
  • USP
  • High throughput (≤15 ml) and bench scale (≤10 L) fed batch bioreactors


The Bacterial Vaccines department is recruiting an Associate Scientist to join the Upstream Processes (USP) team as a multi-parallel microbioreactor operation specialist. You will support the Bacterial Vaccines project teams by applying your understanding of professional practices of bioprocess development for vaccine candidate manufacturing. Your function is responsible for the preparation and operation of a multi-parallel microbioreactor unit fit for bacterial culture and validating the experimental outcome in larger bioreactor units. Experimental work will also include sample preparation, analysis, sample management and data processing. Cross-functional communication with internal and external stakeholders and support is a pivotal part of the job function.

Your main responsibilities will be:
  • Experimental planning and preparation;
  • Bioreactor operation, sampling, and sample analysis;
  • Data analysis and interpretation;
  • Documentation in electronic laboratory notebook and experimental reports;
  • Stakeholder management.

Who we're looking for

The ideal candidate has a B.Sc. or M.Sc. in biotechnology, bioengineering, and/or microbiology with at least 3 years of hands-on experience in Life Sciences industry.
Other requirements are:
  • Bacterial culture activities at biosafety level 1 and 2, incl. genetically modified organisms (GMOs);
  • USP process operation, characterisation, and development;
  • Operation of high throughput (≤15 ml) and bench scale (≤10 L) fed batch bioreactors, and proficiency handling related software;
  • Affinity with conditional based equipment process programming/basic programming principles;
  • Affinity with MS Office, statistical software, databases, sample management programming and alike.


The Bacterial Vaccines department is working on the discovery- and early development of novel vaccines for bacterial infectious diseases. It strives to address unmet medical needs, such as bacteremia (sepsis) and nosocomial infections. Projects at the Bacterial Vaccines department are primarily structured on scientific- and technical collaboration with external biotechnology partners (governmental and industrial) that are innovative leaders in their field. This working process includes ‘state of the art’ vaccine discovery, with subsequent in vivo evaluation of these vaccine candidates in animal models for immunogenicity and/or efficacy. In addition, manufacturing processes are optimised and established, and the resulting clinical trial material is evaluated in human clinical studies.

Company profile

Janssen Vaccines & Prevention B.V. is part of Johnson & Johnson, one of the biggest and most respected health care companies in the world. They are dedicated to bringing meaningful innovation to global health. Their teams focus on the discovery, development, manufacturing, and marketing of novel vaccines to prevent some of the most devastating and complex infectious diseases. These range from respiratory infections like respiratory syncytial virus (RSV) to human immunodeficiency virus (HIV) and pathogens of global concern, such as Ebola and COVID-19.
In this organisation, entrepreneurial people are working in a dynamic culture in which innovation and a 'can do' state of mind are of crucial importance. They are continuously looking for enthusiastic, talented people who have the ambition to develop themselves and can be of value to Janssen. The offices of Janssen Vaccines & Prevention are located in Leiden, The Netherlands.

Additional vacancy information

Contract:Temporary contract with CLS Services
Education:HBO/BSc. WO/MSc.
Employment terms:Project for at least 1 year
Salary: 45000-60000 euro
Publication date:31-10-2023
Location:View location with Google Maps
Contactperson:Claudia Erwich-Faaij
+31 (0)88 22 77 555

CLS Services is a leading professional recruitment agency, specialised in the recruitment and secondment of people with a background in chemistry & life sciences.